WASHINGTON – Today, the U.S. Drug Enforcement Administration, with the cooperation of the U.S. Attorney’s Office for the Eastern District of New York, announced the seizure of more than 200 website domains tied to an India-based transnational criminal organization (TCO) working within the United States and allegedly responsible for at least six fatal and four non-fatal overdoses. The TCO tied to these illegal online pharmacies has been under investigation by DEA’s Rocky Mountain Field Division since 2022.
Beginning on January 27, 2026, DEA field offices throughout the United States conducted multiple operations leading to the arrest of four individuals along with the issuance of five Immediate Suspension Orders (ISO) and one Order to Show Cause (OTSC), both of which are administrative actions taken against DEA registrants in order to protect the public from dangers to public health or safety. These actions were in addition to the U.S. Government shutting down more than 200 online pharmacies accused of filling hundreds of thousands of orders of diverted pharmaceuticals and counterfeit pills without valid prescriptions.
Under the Controlled Substances Act (CSA), DEA regulates the handling, storage, and distribution of controlled substances in the custody of pharmacies. The CSA stipulates that pharmacies are only authorized to dispense controlled substances upon receipt of a valid prescription, issued for a legitimate medical purpose, by an individual practitioner acting in the usual course of his or her professional practice.
Investigators determined the operators of these online pharmacies and their co-conspirators were illegally dispensing and shipping diverted medications, without valid prescriptions, to customers throughout the United States, violating the CSA and dangerously infiltrating a closed system of distribution intended to keep patients safe.
Over the course of this investigation, DEA identified thousands of customers who purchased medication through these online pharmacies. Subsequently, DEA has sent more than 20,000 letters to the public requesting information in support of this ongoing investigation.
“This case demonstrates how foreign-based traffickers exploit our healthcare system, hide behind the internet, and use people inside the United States to move dangerous drugs under the guise of legitimate commerce,” said DEA Administrator Terrance Cole. “Illegal online pharmacies put poison in American communities. They sell counterfeit and unapproved pills and do not care who gets hurt or who dies. Actions like this save lives. They protect the American people. If you run these sites, supply them, move the money, ship the product, or help them operate, we will find you, we will dismantle your operations, and we will hold you fully accountable under U.S. law.”
Leveraging its global reach, DEA actively collaborates with our Government of India law enforcement partners to identify, investigate, and dismantle dangerous criminal organizations that engage in these types of illegal drug trafficking operations. Through joint operations, the DEA will continue to pursue significant enforcement actions against illicit pharmaceutical distributors at the source and remains steadfast in its efforts to disrupt the flow of illicit pharmaceuticals that threaten public health and safety of American citizens.
DEA issued a Public Service Announcement in 2024 warning Americans about an increase in illegal online pharmacies. Many of these online pharmacies sold and shipped counterfeit pills made with fentanyl to unsuspecting customers in the United States who believed they were purchasing legitimate medications from legitimate pharmacies.
Illegal online pharmacies often use U.S.-based website addresses and professional-looking designs to appear legitimate when, in fact, they are not. These companies operate illegally, deliberately deceiving American customers into believing they are legally purchasing safe, regulated medications. Many of the sites taken down as part of Operation Meltdown claimed to be legitimate, based in the U.S., and FDA-approved, but DEA’s investigation determined operators of these sites were often working with drug traffickers to fulfill online orders with counterfeit pills or diverted pharmaceuticals. These counterfeit medications are often made with fentanyl or methamphetamine and taking them can lead to serious health risks, including harmful side effects, ineffective treatment, and even death.
DEA’s One Pill Can Kill campaign reminds the public that the only safe prescription medications are those prescribed by a licensed medical provider and dispensed by a trusted pharmacy.
As online pharmacies increase in popularity, patients are encouraged to remain vigilant when purchasing medication online. It can be difficult to identify an illegal online pharmacy, so here are some possible red flags that may indicate an online pharmacy is not legitimate:
- Sells prescription drugs without requiring a valid prescription from a healthcare provider
- Offers much cheaper prices than what is typically seen in the market
- Lists prices in a foreign currency
- Does not contain proof of a valid pharmacy state license or DEA registration
- Medicine arrives in broken or damaged packaging or in a foreign language
- Medicine does not have an expiration date or is expired
- Medicine looks different from what you have received in the past from your trusted pharmacist
Consumers may visit the U.S. Food and Drug Administration’s BeSafeRx campaign page for information on how to safely buy prescription medication online and how to locate a state-licensed online pharmacy. You can also contact your state board of pharmacy to verify a pharmacy’s license.
This case is being prosecuted by the U.S. Attorney’s Office for the Eastern District of New York.



